MSD Animal Health Bravecto 1400mg (Fluralaner) 12-Week Long-Acting Chewable Tick & Flea Control Tablet for Extra-Large & Giant Dogs (40 to 56 kg, 1 Chewable Tablet)

Active Pharmaceutical Profile & Mechanism of Action

Active ConstituentStrength per UnitPharmacological ClassMode of Action & Clinical EfficacyFluralaner1400 mgSystemic Isoxazoline EctoparasiticidePotently and selectively antagonizes GABA- and L-glutamate-gated chloride channels in arthropods. This triggers uncontrolled continuous nerve firing, flaccid paralysis, and rapid death of fleas, ticks, and mites while remaining well-tolerated by mammalian hosts. Fleas die within 2 hours; ticks die within 12 hours.Flavored Excipientsq.s.Palatability MatrixHighly palatable, chewable matrix designed for voluntary oral acceptance

Clinical Indications

• Treatment and 12-week sustained prevention of flea infestations (Ctenocephalides felis and Ctenocephalides canis).

• Treatment and control of tick infestations (Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor reticulatus, Haemaphysalis spp.).

• Secondary prevention of tick-borne hemoprotozoan diseases (Canine Babesiosis, Ehrlichiosis, Anaplasmosis).

• Treatment and control of Demodectic mange (Demodex canis) and Sarcoptic mange (Sarcoptes scabiei).

• Treatment of ear mite infestations (Otodectes cynotis).

• Prevention of flea-transmitted tapeworm (Dipylidium caninum) infections.

• Strategic management of Flea Allergy Dermatitis (FAD).

Dosage & Administration Guidelines

Administer orally once every 12 weeks (3 months) as directed by your veterinarian.

• Target Body Weight Range: Formulated for extra-large and giant dogs weighing >40 kg to 56 kg.

• Target Dose: Provides the recommended clinical dose of 25 mg to 56 mg Fluralaner per kg body weight.

• Administration Instructions:

  • Always give with food or immediately after a meal. Fluralaner's bioavailability is significantly higher when administered with food, and giving it alongside meals reduces the risk of mild gastrointestinal upset.

  • Offer the chewable tablet directly by hand as a treat, or mix it into a portion of regular food. Confirm that your dog swallows the full tablet.

  • Do not split or crush the tablet.

• Bathing & Swimming: Zero restrictions. Dogs can be bathed, shampooed, or allowed to swim immediately before or after dosing without affecting efficacy.

Bravecto Weight-Based Product Variant Guide

Variant PackagingFluralaner ContentBody Weight BandRepresentative BreedsYellow Box112.5 mg2 kg to 4.5 kgChihuahua, Pomeranian, Toy Poodle, Yorkshire TerrierOrange Box250 mg4.5 kg to 10 kgShih Tzu, Pug, French Bulldog, Dachshund, Lhasa ApsoGreen Box500 mg>10 kg to 20 kgBeagle, Cocker Spaniel, Medium Indie / Pariah, SpitzBlue Box1000 mg>20 kg to 40 kgLabrador Retriever, Golden Retriever, German Shepherd, BoxerPink Box (This Product)1400 mg>40 kg to 56 kgRottweiler, Great Dane, Saint Bernard, Mastiff, Cane Corso

Product Specifications

ParameterDetailsBrandMSD Animal Health (Intervet India Pvt. Ltd. / Merck)Product Trade NameBravecto 1400mg Chewable Tablet for Extra-Large & Giant DogsActive CompositionFluralaner 1400 mgDosage FormFlavored Oral Chewable TabletPack Size1 Chewable Tablet per Box (Pink Pack)Duration of ActionUp to 12 Weeks (3 Months) per tabletTarget SpeciesDogs Only (Weight: >40 kg to 56 kg; Age: 8 weeks and older)Therapeutic ClassIsoxazoline EctoparasiticidePrescription StatusSchedule H Veterinary Prescription Medicine (Valid Rx required at PetMitra checkout)

Safety Warnings, Precautions & Storage

• For canine veterinary oral use only. Do NOT administer to cats. (Cat Bravecto is a distinct topical formulation).

• Weight Accuracy: Confirm your dog’s weight prior to selection. Dogs under 40 kg should receive the 1000 mg or 500 mg variants to prevent over-dosing. Dogs over 56 kg require an appropriate combination of tablets as directed by a veterinarian.

• Puppy Restrictions: Safe for puppies from 8 weeks of age and weighing at least 2 kg.

• Neurological History: Isoxazoline-class medications should be used with caution in dogs with a history of seizures, epilepsy, or tremors. Consult your veterinarian for a full clinical evaluation prior to administration.

• Breeding, Pregnancy & Lactation: Clinically approved and safe for breeding males, pregnant bitches, and lactating mothers.

• Vomiting Management: If your dog vomits within 1 hour of administration, consult your veterinarian regarding re-dosing.

• Storage: Store below 30°C in the original packaging away from direct sunlight and moisture. Keep strictly out of reach of children and household pets