MSD Animal Health Bravecto 250mg (Fluralaner) 12-Week Long-Acting Chewable Tick & Flea Control Tablet for Small Dogs (4.5 to 10 kg, 1 Chewable Tablet)

Active Pharmaceutical Profile & Mechanism of Action

Active ConstituentStrength per UnitPharmacological ClassMode of Action & Clinical EfficacyFluralaner250 mgSystemic Isoxazoline EctoparasiticidePotently and selectively antagonizes GABA- and L-glutamate-gated chloride channels in arthropods. This triggers uncontrolled continuous nerve firing, flaccid paralysis, and rapid death of fleas, ticks, and mites while remaining well-tolerated by mammalian hosts. Fleas die within 2 hours; ticks die within 12 hours.Flavored Excipientsq.s.Palatability MatrixHighly palatable, beef-flavored chewable matrix designed for voluntary oral acceptance

Clinical Indications

• Treatment and 12-week sustained prevention of flea infestations (Ctenocephalides felis and Ctenocephalides canis).

• Treatment and control of tick infestations (Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor reticulatus, Haemaphysalis spp.).

• Secondary prevention of tick-borne hemoprotozoan diseases (Canine Babesiosis, Ehrlichiosis, Anaplasmosis).

• Treatment and control of Demodectic mange (Demodex canis) and Sarcoptic mange (Sarcoptes scabiei).

• Treatment of ear mite infestations (Otodectes cynotis).

• Prevention of flea-transmitted tapeworm (Dipylidium caninum) infections.

• Strategic management of Flea Allergy Dermatitis (FAD).

Dosage & Administration Guidelines

Administer orally once every 12 weeks (3 months) as directed by your veterinarian.

• Target Body Weight Range: Formulated for small dogs weighing 4.5 kg to 10 kg.

• Target Dose: Provides the recommended clinical dose of 25 mg to 56 mg Fluralaner per kg body weight.

• Administration Instructions:

  • Always give with food or immediately after a meal. Fluralaner's bioavailability is significantly higher when administered with food, and giving it alongside meals reduces the risk of mild gastrointestinal upset.

  • Offer the chewable tablet directly by hand as a treat, or mix it into a portion of regular food (or tuck inside paneer, chicken, or curd). Confirm that your dog swallows the full tablet.

  • Do not split or halve the tablet. Dosing is calibrated to the whole tablet for this weight band.

• Bathing & Swimming: Zero restrictions. Dogs can be bathed, shampooed, or allowed to swim immediately before or after dosing without affecting efficacy.

Bravecto Weight-Based Product Variant Guide

Variant PackagingFluralaner ContentBody Weight BandRepresentative BreedsYellow Box112.5 mg2 kg to 4.5 kgChihuahua, Pomeranian, Toy Poodle, Yorkshire TerrierOrange Box (This Product)250 mg4.5 kg to 10 kgShih Tzu, Pug, French Bulldog, Dachshund, Lhasa Apso, Indian SpitzGreen Box500 mg>10 kg to 20 kgBeagle, Cocker Spaniel, Medium Indie / Pariah, SpitzBlue Box1000 mg>20 kg to 40 kgLabrador Retriever, Golden Retriever, German Shepherd, BoxerPink Box1400 mg>40 kg to 56 kgRottweiler, Great Dane, Saint Bernard, Mastiff

Product Specifications

ParameterDetailsBrandMSD Animal Health (Intervet India Pvt. Ltd. / Merck)Product Trade NameBravecto 250mg Chewable Tablet for Small DogsActive CompositionFluralaner 250 mgDosage FormFlavored Oral Chewable TabletPack Size1 Chewable Tablet per Box (Orange Pack)Duration of ActionUp to 12 Weeks (3 Months) per tabletTarget SpeciesDogs Only (Weight: 4.5 kg to 10 kg; Age: 6 months and older / min. 2 kg)Therapeutic ClassIsoxazoline EctoparasiticidePrescription StatusSchedule H Veterinary Prescription Medicine (Valid Rx required at PetMitra checkout)

Safety Warnings, Precautions & Storage

• For canine veterinary oral use only. Do NOT administer to cats. (Cat Bravecto is a distinct topical formulation).

• Age & Weight Limits: Not for puppies under 6 months of age or dogs weighing less than 4.5 kg (use the 112.5 mg variant for dogs 2 to 4.5 kg).

• Neurological History: Isoxazoline-class medications should be used with caution in dogs with a history of seizures, epilepsy, or tremors. Consult your veterinarian for a full clinical evaluation prior to administration.

• Breeding, Pregnancy & Lactation: Clinically approved and safe for breeding males, pregnant bitches, and lactating mothers.

• Vomiting Management: If your dog vomits within 1 hour of administration, consult your veterinarian regarding re-dosing.

• Storage: Store below 30°C in the original blister packaging away from direct sunlight and moisture. Keep strictly out of reach of children and household pet