Intas Synopet Advanced Chondroprotective, Joint Care & Anti-Inflammatory Nutritional Powder for Dogs & Cats

Active Formulation Matrix & Pharmacological Actions (Per 4g Scoop)

Active Nutrient / CofactorConcentration (Per 4g)Pharmacological ClassTherapeutic Target & Biological Mode of ActionGlucosamine HCl440.92 mgAmino Monosaccharide PrecursorStructural building block for GAGs and hyaluronic acid; stimulates chondrocytes to synthesize articular matrix.Chondroitin Sulfate352.74 mgSulfated Glycosaminoglycan (GAG)Binds water molecules within the cartilage matrix; inhibits collagenases and elastases to preserve joint cushion.Methyl Sulfonyl Methane (MSM)200.00 mgOrganic Sulfur DonorSupplies bioavailable sulfur for collagen cross-linking; downregulates inflammatory cytokine release in synovia.EPA & DHA (Omega-3 Fatty Acids)50.00 mgPolyunsaturated Fatty Acids (PUFA)Replaces arachidonic acid in cell membranes; downregulates Leukotriene $B_4$ and Prostaglandin $E_2$ joint inflammation.Bromelain18.00 mgProteolytic Plant EnzymeCleaves inflammatory kinins and fibrin deposits; reduces periarticular soft-tissue edema and post-traumatic swelling.Curcumin6.30 mgBioactive Curcuminoid PolyphenolInhibits NF-$\kappa$B transcription; suppresses COX-2 and iNOS enzymes to relieve chronic joint discomfort.Manganese (as Manganese Glycinate)40.00 mgOrganic Trace Mineral ChelateEssential cofactor for glycosyltransferase; promotes proteoglycan synthesis and accelerates bone fracture callus formation.Ascorbic Acid (Coated Vitamin C)30.00 mgCollagen Biosynthesis CofactorHydroxylates proline into hydroxyproline during fibrillar collagen synthesis; protects synovia against lipid peroxidation.Vitamin E (dl-Alpha Tocopheryl Acetate)10.00 IUMembrane AntioxidantProtects chondrocyte phospholipid membranes against free-radical degradation in chronically inflamed joints.

Clinical Veterinary Indications

• Medical management and nutritional support of Canine and Feline Osteoarthritis (OA) and degenerative joint disease (DJD).

• Developmental orthopedic conditions: Hip Dysplasia, Elbow Dysplasia, and osteochondrosis dissecans (OCD).

• Orthopedic surgical convalescence: post-cruciate ligament reconstruction (TPLO/TTA), FHO, and patella realignment.

• Accelerating bone union, mineral deposition, and callus stability following acute bone fractures.

• Relieving morning stiffness, "bunny-hopping" gait, struggle rising from recumbency, and reluctance to jump or climb stairs.

• Prophylactic joint support for athletic agility dogs, working dogs, and fast-growing large/giant breeds.

Comparison: Intas Synopet Powder vs. Synopet HA Tablets vs. Basic Glucosamine Chews

Feature / MetricIntas Synopet Powder (Current)Intas Synopet HA TabletsGeneric Glucosamine ChewsFormat120g Oral Mixable Powder (with scoop)Chewable Scored TabletsFlavored soft treatsCore GAGsGlucosamine HCl + Chondroitin SulfateGlucosamine + Chondroitin + Hyaluronic AcidGlucosamine aloneEnzymatic & Herbal Anti-InflammatoryBromelain + CurcuminDevil's Claw / Boswellia extractsNoneOmega-3s IncludedYes (EPA + DHA 50mg)VariableAbsentFracture & Callus SupportHigh (Manganese Glycinate 40mg + Vit C)ModerateLowEase of Dosing for Refractory PetsExcellent (Mixes in wet food, curd, broths)Good for treat eaters; tough for pill-spittersEasy treats

Dosage & Administration Guidelines

Administer orally once daily using the measuring scoop provided (1 level scoop = 4 grams). Mix thoroughly into regular wet food, boiled meat, kibble, curd, or a small amount of warm water:

• Standard Clinical Daily Dosing Schedule:

Pet Category & Body WeightDaily Recommended QuantityScoop EquivalentClinical ContextCats up to 5 kg2.0 grams1/2 ScoopSenior cats, chronic jump hesitationCats above 5 kg4.0 grams1 Level ScoopLarge cats (Maine Coons, mature cats)Dogs up to 10 kg (Small Breeds)4.0 grams1 Level ScoopPugs, Shih Tzus, Lhasa Apsos, BeaglesDogs 10 kg to 20 kg (Medium Breeds)6.0 grams1.5 ScoopsCocker Spaniels, Indies, FrenchiesDogs above 20 kg (Large & Giant Breeds)8.0 grams2 Level ScoopsLabradors, Retrievers, GSDs, Rottweilers

• Administration Instructions:

  • Loading Phase vs. Maintenance: In pets with severe stiffness or chronic mobility loss, administer the standard recommended daily dose for 4 to 6 consecutive weeks to saturate cartilage and synovial fluid stores. Once clinical improvement (easier gait, increased playfulness) is established, your veterinarian may adjust to an alternate-day maintenance schedule.

  • Post-Surgical / Fracture Protocol: Start supplementation as soon as the pet resumes oral feeding post-surgery and continue uninterrupted for at least 8 to 12 weeks alongside orthopedic re-checks.

Product Specifications

ParameterDetailsBrandIntas Pharmaceuticals Ltd. (Intas Animal Health - PET Division)Product Trade NameSynopet Joint Care Nutritional PowderProduct ClassificationAdvanced Multi-Action Veterinary Chondroprotective & Orthopedic SupplementActive Composition (per 4g)Glucosamine HCl 440.92mg, Chondroitin Sulfate 352.74mg, MSM 200mg, EPA/DHA 50mg, Curcumin 6.3mg, Bromelain 18mg, Manganese Glycinate 40mg, Ascorbic Acid 30mg, Vitamin E 10 IUDosage FormOral Nutritional Powder with Measuring ScoopPackaging Size120 g Plastic JarTarget SpeciesDogs and Cats of all life stagesTherapeutic ClassChondroprotective, Anti-Arthritic & Musculoskeletal Convalescent SupplementPrescription StatusOTC Veterinary Nutritional Supplement (No Rx required)

Safety Warnings, Precautions & Storage

• Nutritional Supplement Classification: Formulated for animal nutritional support; does not replace immediate veterinary surgical fixation for acute fractures or unstable joint luxations.

• Diabetic Patient Monitoring: Glucosamine is an amino sugar. While systemic impacts on glycemic control are generally minimal, routine blood glucose monitoring is recommended in diabetic dogs and cats during the first few weeks of therapy.

• Pre-Surgical Antiplatelet Caution: High-dose marine Omega-3 fatty acids and bromelain possess mild anti-inflammatory and fibrinolytic properties. Discontinue elective use 10 to 14 days prior to major scheduled soft-tissue surgeries under veterinary guidance.

• Shellfish Allergy Precaution: Glucosamine is commonly synthesized from crustacean chitin. Use with caution in pets with documented severe shellfish hypersensitivity.

• Storage: Store below 25°C in a cool, dry place protected from heat, direct sunlight, and moisture. Keep the jar lid tightly sealed when not in use to avoid powder caking. Keep strictly out of reach of children and domestic pets.