Mankind PetStar V Diet Clinical UroRenal Management Dry Dog Food

Active Formulation Matrix & Physiological Modes of Action

Nutritional Component GroupSpecific Ingredients / ActivesRenal & Urological Mode of ActionHigh-Biological Value ProteinsHydrolyzed Chicken Protein & Dehydrated ChickenSupplies essential amino acids to maintain lean muscle while minimizing nitrogenous uremic waste buildup in the bloodstream.Urinary Acidifier & Crystal DissolverDL-MethionineModulates urinary pH to a therapeutic range, dissolving magnesium ammonium phosphate (struvite) stones and inhibiting new crystal formation.Urothelial Protectant & Anti-AdhesiveDried Cranberries (Vaccinium macrocarpon)Proanthocyanidins prevent E. coli fimbriae from adhering to the urothelium, reducing the risk of ascending bacterial cystitis.Natural Diuretic & Renal DetoxifierDried Stinging Nettle (Urtica dioica)Enhances renal solute clearance and gentle flushing; provides anti-inflammatory flavonoids to soothe irritated urinary tissues.Metabolic & Lean Mass CatalystL-CarnitineFacilitates mitochondrial fatty acid transport for energy; helps prevent uremic muscle wasting without requiring excess protein intake.Renal Hemodynamic LipidsAlgae Oil & Salmon Oil (DHA & EPA)Displaces inflammatory eicosanoids; reduces glomerular hypertension and slows renal tubulointerstitial fibrosis.Enteric Uremic Toxin BindersPsyllium Husk, Dried Beet Pulp, Hydrolyzed Yeast (MOS) & FOSTraps urea, ammonia, and nitrogenous metabolites in the gut for fecal excretion, reducing the filtration burden on compromised kidneys.Phytobiotic Anti-Inflammatory ShieldDried Curcuma, Rosemary, Citrus & Yucca SchidigeraCurcumin downregulates inflammatory NF-$\kappa$B; citrus flavonoids provide antioxidant protection; Yucca binds fecal ammonia.

Clinical Veterinary Indications

• Early and moderate stages of Chronic Kidney Disease (CKD / IRIS Stages 1, 2, and 3 under monitoring).

• Dietary management, dissolution, and long-term prevention of sterile struvite uroliths (magnesium ammonium phosphate).

• Supportive nutritional therapy for recurrent bacterial urinary tract infections (UTIs) and cystitis.

• Management of dogs exhibiting signs of lower urinary tract disease (dysuria, stranguria, hematuria, pollakiuria).

• Maintenance diet for canines requiring controlled mineral levels and enteric nitrogen reduction under veterinary direction.

Comparison: Mankind PetStar UroRenal vs. Royal Canin Renal vs. Hill's Prescription Diet k/d & c/d

Clinical ParameterMankind PetStar V Diet UroRenalRoyal Canin Veterinary RenalHill's Prescription Diet k/d + c/d CaninePrimary Dual TargetRenal Support + Struvite CareRenal Function SupportRenal Function (k/d) OR Urinary Care (c/d)Protein ArchitectureHydrolyzed & Dehydrated ChickenDehydrated Pork & Poultry / MaizeBrewers Rice, Egg Product, Pork FatUrinary AcidifierDL-Methionine includedAbsent (Aims for alkaline urine)Calibrated per formulationBotanical Cranberry & NettleYes (Dried Cranberry + Stinging Nettle)AbsentAbsentMarine Omega-3 SourcesSalmon Oil + Pure Marine Algae OilFish oilFish oilEnteric Toxin Binding FibersPsyllium + Beet Pulp + MOS/FOSBeet pulp + FOSBeet pulpCountry of ManufactureWales, United Kingdom (BRCGS Certified)France / South AfricaUSA / Europe

Feeding Guidelines & Daily Dosage Chart

Divide total daily rations into 2 to 3 separate meals. Ensure clean drinking water is accessible in multiple clean bowls to support healthy urine dilution:

7 to 10-Day Transition Schedule (Mandatory):

• Days 1–2: 25% PetStar UroRenal + 75% Current Food

• Days 3–4: 50% PetStar UroRenal + 50% Current Food

• Days 5–6: 75% PetStar UroRenal + 25% Current Food

• Day 7–10 Onward: 100% Mankind PetStar V Diet UroRenal Management

Weight-Based Daily Feeding Guide:

Dog Body Weight BracketRecommended Daily Allowance (g/day)Clinical Management Strategy1 kg to 5 kg (Toy Breeds)30 g – 85 gDivide into 3 small feedings; ensure fresh water bowl5 kg to 10 kg (Small Breeds)85 g – 145 gDivide into 2–3 feedings10 kg to 20 kg (Medium Breeds)145 g – 245 gDivide into 2 feedings20 kg to 35 kg (Large Breeds)245 g – 375 gDivide into 2 feedings35 kg to 50 kg (Large / Giant)375 g – 490 gDivide into 2 feedings50 kg to 80 kg (Giant Breeds)490 g – 680 gDivide into 2 feedings

• Hydration Protocol: For renal convalescence, soaking the kibble in lukewarm water for 10 minutes before feeding increases daily voluntary fluid consumption and promotes urinary bladder flushing.

Product Specifications

ParameterDetailsBrandMankind Pharma Ltd. (Pet Mankind - PetStar Division)Product Trade NamePetStar V Diet UroRenal Management Dry Dog FoodProduct ClassificationClinical Veterinary Prescription Diet / UroRenal Therapeutic FoodPrimary ProteinsHydrolyzed Chicken Protein & Dehydrated ChickenKey Botanical ActivesDried Cranberries, Dried Stinging Nettle, Dried Curcuma, Dried RosemaryKey Therapeutic AgentsDL-Methionine, L-Carnitine, Salmon Oil, Algae Oil, Psyllium HuskFormExtruded Dry Food KibbleCountry of ManufactureWales, United Kingdom (BRCGS-Certified Facility)Target Species & Life StageAdult Dogs requiring renal support, urinary tract care, and struvite dissolutionTherapeutic ClassNephro-Protective, Struvite Dissolving & Urothelial Supportive DietPrescription StatusVeterinary Therapeutic Diet (Recommended under veterinary guidance)

Safety Warnings, Precautions & Contraindications

• Struvite vs. Oxalate Distinction: Formulated specifically to manage struvite urolithiasis by promoting mild urinary acidification. Contraindicated in dogs with active Calcium Oxalate, Ammonium Urate, or Cystine urolithiasis, or in cases of severe metabolic acidosis.

• Regular Monitoring: Renal values (serum Creatinine, BUN, symmetric dimethylarginine [SDMA], Phosphorus) and urine specific gravity/pH should be re-evaluated regularly by a licensed veterinarian.

• Fresh Water Availability: Adequate hydration is vital for renal filtration and urinary dilution. Fresh, clean drinking water must be available at all times.

• Storage Instructions: Store in a cool, dry place away from direct sunlight, moisture, and pests. Reseal the package tightly after each use to keep kibble fresh and protect active marine oils from oxidation. Keep strictly out of reach of children and domestic pets.