Savavet Kiwof Puppy (Pyrantel Pamoate 14.4mg/ml + Febantel 15mg/ml) Broad-Spectrum Liquid Deworming Suspension for Puppies & Young Dogs (15ml with Calibrated Syringe/Dropper)

Active Pharmaceutical Profile & Clinical Mechanism

Active ConstituentConcentration / mlPharmacological ClassTherapeutic Target & ActionPyrantel Pamoate14.4 mgTetrahydropyrimidine NematocideInduces persistent depolarization of parasite nicotinic receptors, causing spastic muscular paralysis in roundworms (Toxocara, Toxascaris) and hookworms (Ancylostoma, Uncinaria). Poorly absorbed systemically, remaining focused in the intestinal tract.Febantel15.0 mgPro-Benzimidazole NematocideRapidly bio-transformed into fenbendazole; inhibits tubulin polymerization and disrupts glucose metabolism, depleting energy stores and starving whipworms (Trichuris vulpis) and larval nematodes.Aqueous Carrier / Excipientsq.s. to 1 mlOral Pediatric VehicleStabilized suspension base formulated for smooth palatability, easy oral measurement, and uniform active dispersion.

Target Parasite Spectrum

• Roundworms (Ascarids): Toxocara canis, Toxascaris leonina (adults and immature larval stages).

• Hookworms: Ancylostoma caninum, Uncinaria stenocephala.

• Whipworms: Trichuris vulpis.

• (Note: This pediatric formulation does not contain praziquantel and does not cover tapeworms. When puppies transition to older juvenile stages or encounter fleas, your veterinarian may transition them to Kiwof Plus / Drontal Plus tablets).

Recommended Pediatric Deworming Schedule

Puppy weights change rapidly during early growth phases. Always weigh your puppy before each dosing session to calibrate volume.

• Standard Dosage Rate: 1 ml suspension per 1 kg body weight as a single oral administration.

Puppy Age RangeRecommended FrequencyClinical Rationale2 Weeks to 12 Weeks (Up to 3 Months)Every 2 Weeks (Weeks 2, 4, 6, 8, 10, 12)Intercepts roundworms passed through placenta/milk before they can mature and shed eggs.3 Months to 6 MonthsOnce Every MonthSustains parasite-free gut development during the active teething and outdoor socialization phase.6 Months to 1 YearOnce Every 3 Months (Quarterly)Maintains digestive protection through late juvenile growth up to skeletal maturity.Above 1 Year of AgeTransition to Adult TabletsSwitch to broad-spectrum adult chewables (Savavet Kiwof Plus or Kiwof Plus XL).

Directions for Administration

1. Shake Well: Shake the bottle vigorously before drawing each dose to ensure uniform active dispersion.

2. Measure Dose: Using the included graduated measuring syringe or dropper, measure 1 ml for every 1 kg of current body weight (e.g., 0.5 ml for a 500g pup, 1.5 ml for a 1.5 kg pup, 3 ml for a 3 kg pup).

3. Administer:

   • Direct Oral Route: Insert the tip of the syringe into the corner of the puppy’s mouth and slowly depress the plunger onto the back of the tongue.

   • Mixed with Food: Can be mixed into a teaspoon of puppy starter mousse, wet food, or curd. Ensure the entire medicated portion is eaten.

4. Fasting: Fasting before or after administration is not required. Giving after a small meal helps prevent transient stomach upset.

Product Specifications

ParameterDetailsBrandSavavet (Sava Healthcare Limited)ManufacturerFinecure Pharmaceuticals Ltd.Product Trade NameKiwof Puppy Deworming SuspensionActive CompositionPyrantel Pamoate 14.4 mg/ml + Febantel 15 mg/mlDosage FormOral Liquid SuspensionNet Volume15 ml Bottle with Calibrated Syringe / DropperTarget SpeciesPuppies & Young Dogs (From 2 weeks of age up to 1 year)Therapeutic ClassPediatric Anthelmintic / Gastrointestinal DewormerPrescription StatusOTC Veterinary Medicated Suspension (Veterinary Supervised)

Safety Warnings, Precautions & Storage

• Canine Pediatric Use Only: Formulated specifically for dogs and puppies. Do NOT administer to cats or kittens (use Savavet Kiwof Cat for feline patients).

• Age Minimum: Do not administer to puppies under 2 weeks of age.

• Pregnancy & Nursing Precautions: Do not administer to pregnant or nursing mothers without explicit veterinary advice. Treat the lactating mother with an approved nursing-safe maternal dewormer under veterinary supervision.

• Drug Interaction Warning: Do not use simultaneously with piperazine compounds, as pyrantel and piperazine have opposing neuromuscular mechanisms and neutralize each other's efficacy.

• Hygiene Alert: Intestinal worms and viable microscopic eggs may pass in the puppy's stool for 24 to 72 hours post-dosing. Clean up waste immediately and wear gloves to prevent zoonotic roundworm transmission (Toxocara canis visceral larva migrans).

• Storage: Store below 25°C in a cool, dry place. Keep protected from direct sunlight. Ensure the cap is tightly closed after each use. Keep strictly out of reach of children and domestic pets.