Intas Melonex 2.5mg Preferential COX-2 Inhibiting NSAID Chewable Tablets for Dogs

Active Pharmaceutical Matrix & Pharmacological Actions

Active ConstituentStrength per TabletPharmacological ClassTarget Pathway & Mode of ActionMeloxicam IP2.5 mgNSAID (Oxicam Class / Preferential COX-2 Inhibitor)Preferentially blocks the inducible COX-2 enzyme, reducing production of inflammatory prostaglandins ($PGE_2$) to relieve pain, swelling, and fever.Chewable Excipient BaseBase q.s. to 1 TabletUncoated Chewable MatrixEnhances aroma and texture to promote voluntary intake and ensure uniform gastric disintegration.

Clinical Veterinary Indications

• Chronic pain, joint inflammation, and stiffness associated with canine osteoarthritis and degenerative joint disease (DJD).

• Musculoskeletal conditions: Cruciate ligament strains, hip or elbow dysplasia, sprains, contusions, and disk-related back pain.

• Post-operative analgesia following orthopedic procedures, soft-tissue surgeries, and dental extractions.

• Acute inflammatory pain from accidental trauma, bite wounds, and soft-tissue swelling.

• Short-term fever reduction (antipyretic) in acute inflammatory conditions under veterinary direction.

Comparison: Intas Melonex 2.5mg Tablets vs. Melonex Oral Suspension vs. Succedal (Carprofen)

Clinical ParameterIntas Melonex 2.5mg Tablets (Current)Intas Melonex Oral Suspension (1.5mg/ml)Alembic Succedal (Carprofen) TabletsActive DrugMeloxicam (2.5 mg)Meloxicam (1.5 mg/ml)Carprofen (50 mg / 100 mg)FormatChewable, uncoated tabletsLiquid suspension with syringeScored chewable tabletsBest Suited ForMedium to large dogs (≥12.5 kg)Small and toy breed dogs (<10 kg)Moderate to severe canine osteoarthritisDosing AdministrationFixed tablet halves/wholesMilliliter-precise weight titrationWeight-banded tablet dosingPrescription StatusSchedule H / Veterinary RxSchedule H / Veterinary RxSchedule H / Veterinary Rx

Dosage & Administration Guidelines

Administer orally strictly as prescribed by your treating veterinarian based on your dog's verified body weight:

• Two-Phase Clinical Dosing Protocol:

  • Day 1 (Initial Loading Dose): 0.2 mg meloxicam per kg body weight as a single dose.

  • Day 2 Onward (Daily Maintenance Dose): 0.1 mg meloxicam per kg body weight once daily.

• Practical Reference Guide for Melonex 2.5mg Tablets:

Dog Body WeightDay 1 Initial Loading Dose (0.2 mg/kg)Day 2 Onward Daily Maintenance (0.1 mg/kg)12.5 kg1 Tablet1/2 Tablet25.0 kg2 Tablets1 Tablet37.5 kg3 Tablets1.5 Tablets50.0 kg4 Tablets2 Tablets

• Administration Instructions:

  • Always administer with or immediately after a meal: Giving on a full stomach protects the gastric mucosal lining.

  • Give once daily at the same time each day.

  • For tiny or toy-breed dogs weighing under 10 kg, consider using Intas Melonex Oral Suspension for precise milliliter dosing.

  • Always ensure fresh drinking water is accessible throughout the treatment period.

Product Specifications

ParameterDetailsBrandIntas Pharmaceuticals Ltd. (Intas Animal Health)Product Trade NameMelonex 2.5mg Chewable TabletsProduct ClassificationVeterinary Non-Steroidal Anti-Inflammatory Drug (NSAID)Active CompositionMeloxicam IP (2.5 mg per tablet)Dosage FormUncoated Chewable Oral TabletsPackaging SizeBlister Strip of 10 Tablets (1x10)Target SpeciesDogs (Strict veterinary prescription required)Therapeutic ClassAnalgesic, Anti-Inflammatory & Antipyretic AgentPrescription StatusSchedule H / Veterinary Prescription Medicine (Rx required)

Safety Warnings, Precautions & Contraindications

• STRICT FELINE WARNING (DO NOT USE IN CATS WITHOUT DIRECT VET RX): Cats metabolize NSAIDs slowly due to deficient glucuronide conjugation pathways. Inadvertent administration of canine doses to cats can cause acute renal failure and may be fatal. Use only dedicated feline-approved pain regimens under veterinary guidance.

• Never Combine with Other NSAIDs or Corticosteroids: Do not administer alongside aspirin, carprofen, firocoxib, prednisolone, or dexamethasone. Combining these agents significantly increases the risk of gastrointestinal ulcers, intestinal perforation, and kidney failure.

• Required Washout Period: When switching between different NSAIDs, observe a washout gap of 5 to 7 days with no pain medication before starting the new drug.

• Pre-Existing Organ Conditions: Contraindicated in dogs with active gastrointestinal ulceration, severe liver or kidney disease, or bleeding disorders.

• Avoid in Dehydrated Dogs: Do not give to hypovolemic or severely dehydrated animals, as reduced renal perfusion increases the risk of kidney damage.

• Warning Signs to Discontinue: Stop medication immediately and contact your veterinarian if you observe: persistent vomiting, dark/tarry stools (melena), yellowing of the eyes/gums (jaundice), severe lethargy, or sudden changes in water consumption and urination.

• Long-Term Monitoring: For dogs receiving long-term arthritis management, schedule routine blood tests (BUN, creatinine, ALT) every 6 months to monitor kidney and liver function.

• Storage: Store below 30°C in a dry place protected from heat, direct sunlight, and moisture. Keep tablets sealed in their original blister pack. Keep strictly out of reach of children and domestic pets.