Intas Synopet HA Advanced Bone, Joint & Cartilage Support Tablets for Dogs & Cats

Active Formulation Matrix & Nutritional Mechanisms (Per Chewable Tablet)

Active Nutrient / BotanicalConcentration per TabBiochemical ClassArticular Target & Physiological RoleGlucosamine HCl450 mgAmino Monosaccharide PrecursorStimulates chondrocyte synthesis of glycosaminoglycans (GAGs) and proteoglycans to rebuild cartilage matrix.Chondroitin Sulphate330 mgSulfated GlycosaminoglycanAttracts water into articular cartilage for compressibility; neutralizes cartilage-degrading enzymes (elastase, hyaluronidase).Methylsulfonylmethane (MSM)200 mgBioavailable Organic SulfurProvides sulfur donor bonds for collagen cross-linking; reduces connective tissue inflammation and discomfort.N,N-Dimethylglycine (DMG)100 mgMethylated Amino Acid DerivativeEnhances cellular oxygen utilization, improves muscle metabolism, and supports immune modulation around joint capsules.EPA & DHA (Omega-3 Fatty Acids)50 mgLong-Chain Polyunsaturated Fatty AcidsCompete with arachidonic acid to downregulate pro-inflammatory prostaglandins ($PGE_2$) and leukotrienes.Hyaluronic Acid (Sodium Hyaluronate)18 mgSynovial GlycosaminoglycanRestores fluid viscosity and lubrication inside joint cavities; acts as a natural shock absorber.Bromelain18 mgProteolytic Plant Enzyme (Pineapple)Breaks down inflammatory kinins and fibrin deposits to alleviate peri-articular soft-tissue swelling.Curcumin6.3 mgStandardized Curcuminoid ExtractPotent botanical antioxidant; inhibits NF-kB activation to suppress joint inflammatory signaling cascades.Manganese Glycinate40 mgEssential Trace Mineral ChelateVital enzymatic cofactor for glycosyltransferases required in cartilage proteoglycan synthesis.Coated Ascorbic Acid (Vitamin C)30 mgHydroxylation Coenzyme AntioxidantEssential cofactor for prolyl and lysyl hydroxylase in collagen fibril synthesis; neutralizes free radicals.

Clinical Veterinary Indications

• Canine osteoarthritis, spondylosis, and degenerative joint disease (DJD) in middle-aged and senior pets.

• Hip dysplasia and elbow dysplasia management in large and giant breed dogs.

• Weak hind legs, morning stiffness, difficulty climbing stairs, and reduced playfulness.

• Skeletal joint and cartilage reinforcement in fast-growing large-breed puppies (Golden Retrievers, Labradors, GSDs).

• Joint protection for working, agility, police, and sporting canines subject to high mechanical impact.

• Convalescent post-operative rehabilitation following orthopedic surgeries (patellar luxation, cruciate repairs, fracture pins).

Comparison: Intas Synopet HA vs. Virbac Canitone Joint Care vs. Basic Glucosamine

ParameterIntas Synopet HA Tablets (Current)Virbac Canitone Joint CareBasic OTC Pet GlucosamineCore FormulationHA + Glucosamine + Chondroitin + MSM + DMG + Curcumin + BromelainType-II Collagen + Glucosamine + BoswelliaGlucosamine + Chondroitin onlyHyaluronic Acid (HA)Yes (18 mg per tablet)Variable / traceNoSynovial LubricationHigh (Direct viscosupplementation)ModerateMildMuscle Oxygenation (DMG)Yes (100 mg per tablet)NoNoEnzyme & Herbal Anti-InflammatoryYes (Bromelain + Curcumin + EPA/DHA)Yes (Boswellia extract)NoSpecies SuitabilityDogs & CatsDogsDogs

Dosage & Administration Guidelines

Administer orally once daily based on your pet's body weight. Can be offered directly by hand as a palatable treat or crushed and mixed into meals:

• Standard Weight-Based Dosing Protocol (1 Tablet per 15 kg Body Weight):

Pet Type & Body Weight RangeRecommended Daily DoseAdministration NotesCats (Adult)1/4 to 1/2 Tablet dailyConsult veterinarian for feline-specific dosingSmall Dogs (< 7.5 kg)1/2 Tablet dailySplit cleanly along scored lineMedium Dogs (7.5 kg to 15 kg)1 Tablet dailyBeagles, Cocker Spaniels, IndiesLarge Dogs (15 kg to 30 kg)2 Tablets dailyLabradors, Boxers, DalmatiansLarge / Giant Dogs (30 kg to 45 kg)3 Tablets dailyGolden Retrievers, German Shepherds, RottweilersGiant Breeds (> 45 kg)4 Tablets dailyGreat Danes, Saint Bernards, Mastiffs

• Administration Instructions:

  • Initial Phase (Loading Period): For pets with severe joint stiffness or advanced osteoarthritis, veterinarians often recommend doubling the maintenance dose for the first 4 to 6 weeks to rapidly saturate joint tissue levels.

  • Maintenance Phase: Once noticeable mobility improvement is observed, reduce to the standard maintenance dose for long-term daily protection.

  • Consistent daily administration for a minimum of 6 to 8 weeks is recommended to evaluate full therapeutic benefits.

Product Specifications

ParameterDetailsBrandIntas Pharmaceuticals Ltd. (Intas Animal Health)Product Trade NameSynopet HA Chewable TabletsProduct ClassificationAdvanced Veterinary Chondroprotective & Synovial Joint SupplementActive CompositionHyaluronic Acid, Glucosamine HCl, Chondroitin Sulphate, MSM, DMG, EPA/DHA, Curcumin, Bromelain, Manganese, Vitamin CDosage FormPalatable Chewable Oral TabletsPackaging SizeBlister Strip of 15 TabletsTarget SpeciesDogs and Cats across all life stagesTherapeutic ClassArticular Chondroprotective, Synovial Lubricant & Joint Mobility TonicPrescription StatusOTC Veterinary Nutritional Supplement (No Rx required)

Safety Warnings, Precautions & Storage

• Veterinary Nutritional Supplement: Formulated for canine and feline dietary joint support. Not intended to replace acute surgical intervention in severe luxations or fractures.

• Synergistic Use with NSAIDs: Synopet HA is non-steroidal and safe to use alongside pain medications like Intas Melonex (Meloxicam). Using Synopet HA long-term often allows veterinarians to lower the maintenance dose of daily NSAIDs.

• Storage: Store below 25°C in a dry place protected from heat, direct sunlight, and moisture. Keep tablets sealed in their original blister strip until administration. Keep strictly out of reach of children and domestic pets.