Savavet Kiwof Plus XL Broad-Spectrum Chewable Deworming Tablets for Large & Giant Dogs (Pack of 10 Tablets

Active Pharmaceutical Profile & Clinical Mechanism

Active MoleculeStrength per XL TabletPharmacological ClassTherapeutic Target & ActionPraziquantel IP175 mgPyrazinoisoquinoline AnticestodalAlters membrane permeability to calcium ions, triggering rapid tetanic contraction and destruction of tapeworm integument (Dipylidium, Taenia, Echinococcus).Pyrantel Pamoate IP504 mgTetrahydropyrimidine NematocideActs as an agonist on nicotinic acetylcholine receptors, inducing depolarizing neuromuscular paralysis in roundworms (Toxocara) and hookworms (Ancylostoma).Febantel IP525 mgPro-Benzimidazole NematocideBiotransformed into fenbendazole; inhibits tubulin polymerization and disrupts glucose metabolism, starving whipworms (Trichuris vulpis) and resistant ascarids.Palatability Excipientsq.s.Oral Chewable BaseFormulated with artificial flavors and disintegrants for voluntary acceptance and rapid breakdown.

Target Parasite Spectrum

• Cestodes (Tapeworms): Dipylidium caninum (flea tapeworm), Taenia hydatigena, Taenia pisiformis, Echinococcus granulosus, Echinococcus multilocularis.

• Ascarids (Roundworms): Toxocara canis, Toxascaris leonina (adult and late immature forms).

• Ancylostomatidae (Hookworms): Ancylostoma caninum, Ancylostoma braziliense, Uncinaria stenocephala.

• Trichuridae (Whipworms): Trichuris vulpis.

• (Note: Kiwof Plus XL is not active against fleas, ticks, or heartworms; pair with Bravecto or Advocate for comprehensive external/vector protection).

Dosage & Administration Guidelines

Administer orally as a single dose strictly according to your dog's current body weight:

• Standard Dosing Ratio: 1 tablet per 35 kg body weight (or 1/2 tablet per 17.5 kg body weight).

Dog Body Weight RangeRecommended Kiwof Plus XL DoseRepresentative Breeds17.5 kg to 20 kg1/2 TabletSmall Labrador, Border Collie, Beagle (heavy), Bull Terrier21 kg to 35 kg1 TabletAdult Labrador, Golden Retriever, German Shepherd, Boxer, Doberman36 kg to 52.5 kg1.5 TabletsRottweiler, Alaskan Malamute, Cane Corso, Rhodesian Ridgeback53 kg to 70 kg2 TabletsGreat Dane, Saint Bernard, English Mastiff, Tibetan Mastiff

• Administration Instructions:

  • Can be offered directly by hand as a chewable treat or tucked into chicken, paneer, or canned food.

  • Confirm that your dog completely chews and swallows the entire tablet.

  • Fasting before or after administration is not required.

• Routine Preventive Frequency:

  • Adult Dogs: Administer once every 3 months (quarterly) for routine maintenance.

  • Confirmed Severe Burden: Repeat after 14 days under veterinary supervision to clear newly emerging larvae.

Product Specifications

ParameterDetailsBrandSavavet (Sava Healthcare Limited)Product Trade NameKiwof Plus XL Chewable Tablets for Large DogsActive CompositionPraziquantel IP 175 mg + Pyrantel Pamoate IP 504 mg + Febantel IP 525 mgDosage FormFlavored Oral Scored Chewable TabletsPack Size1 Blister Strip x 10 TabletsTarget SpeciesLarge and Giant Dogs (Weighing 17.5 kg and above)Therapeutic ClassHigh-Potency Broad-Spectrum AnthelminticPrescription StatusSchedule H Veterinary Prescription Medicine (Valid Rx required at PetMitra checkout)

Safety Warnings, Precautions & Storage

• Canine Specific: Formulated exclusively for dogs. Do NOT administer to cats.

• Weight Threshold: Not intended for small dogs or puppies weighing under 17.5 kg (use regular Savavet Kiwof Plus dosed at 1 tab/10 kg or Kiwof Puppy Suspension for smaller animals).

• Pregnancy & Lactation: Do not use during the 1st and 2nd trimesters of pregnancy due to febantel's potential teratogenic risks at high doses. Use during late gestation or lactation only under explicit veterinary guidance.

• Drug Interactions: Do not administer concurrently with piperazine compounds, as pyrantel and piperazine have opposing neuromuscular mechanisms.

• Tapeworm Observation: Tapeworms disintegrate internally; do not expect to see intact tapeworms in the stool. Dead roundworms or hookworms may be passed over the subsequent 48 hours.

• Storage: Store below 25°C in a dry place. Protect from heat, direct sunlight, and moisture. Keep unused tablet halves sealed in the blister and administer within 7 days. Keep strictly out of reach of children and household pets.