Savavet Fiprofort (Fipronil 0.25% w/v) Broad-Spectrum Ectoparasitic Tick, Flea & Chewing Lice Control Spray for Dogs & Cats (Available in 100ml & 250ml Calibrated Metered Spray Bottles)

Active Formulation Matrix & Ectoparasitic Pharmacology

Parameter / ConstituentSpecificationPharmacological Mechanism & Clinical RoleActive MoleculeFipronil (0.25% w/v / 2.5 mg/ml)Non-systemic phenylpyrazole broad-spectrum insecticide and acaricide.Primary Target ReceptorInsect GABA-Gated & GluCl ChannelsSelectively binds insect neural chloride channels, causing uncontrolled neuronal hyper-excitation and parasite death without mammalian neurotoxicity.Tissue DistributionCutaneous Sebum & Sebaceous GlandsNon-systemically absorbed; dissolves across the lipid bilayer and deposits in hair follicles to provide weeks of residual action.Residual Efficacy DurationTicks: Up to 30 Days; Fleas: Up to 60–90 DaysVaries according to environmental challenge and frequency of shampooing.Carrier BaseAlcoholic Evaporative VehiclePromotes rapid evaporation, leaving the active molecule bonded to the epidermal lipid layer without a greasy residue.

Ectoparasite Spectrum & Targeted Pathogens

Parasite CategoryTarget Species CoveredClinical Threat & Vector Pathology PreventedTicks (Acarids)Rhipicephalus sanguineus (Brown Dog Tick), Haemaphysalis spp., Ixodes spp.Vectors of Babesia canis/gibsoni, Ehrlichia canis, Anaplasma phagocytophilum, and tick paralysis.Fleas (Insects)Ctenocephalides felis (Cat Flea), Ctenocephalides canis (Dog Flea)Intermediate host for Dipylidium caninum (tapeworm); triggers severe Flea Allergy Dermatitis (FAD).Chewing LiceTrichodectes canis (Dogs), Felicola subrostratus (Cats)Causes severe scaling, pruritus, alopecia, and unthrifty coat condition.Mite Aid (Supportive)Sarcoptes scabiei (Sarcoptic Mange aid under vet guidance)Supplementary topical knockdown of surface-burrowing mites in early infestations.

Comparison: Savavet Fiprofort Spray vs. Fipronil Spot-On vs. Oral Isoxazoline Chewables

Feature / MetricSavavet Fiprofort Spray (0.25%)Fipronil Spot-On Pipettes (9.7%–10%)Oral Chewables (Sarolaner / Fluralaner)Application TypeWhole-body topical metered sprayLocalized topical spot-on (back of neck)Oral chewable systemic tabletParasite Feeding RequiredNo (Direct cuticular contact kill)No (Direct cuticular contact kill)Yes (Parasite must take a blood meal)Immediate KnockdownVery Fast (Immediate contact with all parasites)Moderate (Spreads across body over 24–48h)Fast once ingested through feedingHeavy Infestation UtilityHighest (Instantly covers high parasite load)Moderate (Better for routine prevention)High systemic clearanceSpecies VersatilityDogs AND Cats in the same bottleSpecies-specific pipettes (Dog vs. Cat)Strictly species-specificPediatric SuitabilityPuppies & Kittens from 8 weeks / light weightsMinimum weight thresholds (usually 1.5–2 kg)Minimum weight thresholds (usually 1.3–2 kg)

Dosage & Calculation Protocol

Therapeutic Application Rate:

• General Dose Rate: Administer 3 ml to 6 ml per kilogram of pet body weight (equivalent to 7.5 mg to 15 mg of active Fipronil per kg).

  • Short-Haired Pets: Use 3 ml per kg (lower end of dose range).

  • Long-Haired, Dense-Coated, or Heavily Infested Pets: Use 6 ml per kg (upper end of dose range) to ensure the solution penetrates through undercoats down to the skin level.

Metered Pump Calibration:

• 100 ml Bottle (Standard Trigger Pump): Approximately 0.5 ml per pump actuation (approx. 6 to 12 pump strokes per kg body weight).

• 250 ml Bottle (High-Output Trigger Pump): Approximately 1.5 ml per pump actuation (approx. 2 to 4 pump strokes per kg body weight).

Step-by-Step Directions for Use

1. Application Environment: Apply outdoors or in a well-ventilated room, away from open flames, gas heaters, or electrical heat sources.

2. Personal Protection: Wear protective waterproof rubber or nitrile gloves during application.

3. Coat Preparation: Ensure the pet's coat is completely dry. Do not apply on damp or wet hair.

4. Spray Technique: Hold the bottle upright at a distance of 10 to 15 cm from the pet. Spray the entire body evenly, ruffling the fur against the natural lay of the coat so the spray wets the hair down to the skin.

5. Coverage Areas: Ensure complete coverage across the back, flanks, abdomen, legs, paws, and base of the tail.

6. Facial & Ear Application (Caution): Never spray directly toward the pet's face, eyes, nose, or mouth. To treat the head, neck, and ear folds, spray Fiprofort onto your gloved hand or a clean cloth and gently rub it over the muzzle, around the eyes, and behind the ears, avoiding direct ocular and mucous membrane contact.

7. Natural Air-Drying: Allow the coat to dry naturally in a well-ventilated area. Do not towel-dry, blow-dry with heat, or rub off the formulation.

8. Prevent Licking: Prevent the pet (and other household pets) from grooming or licking the treated areas until the coat is completely dry (usually 30 to 45 minutes). Use an Elizabethan collar (E-collar) if necessary during drying.

Critical Safety & Bathing Protocols

• The 48-Hour Bathing Rule: Do not bathe the pet with shampoo 48 hours before or 48 hours after application. Shampooing strips the stratum corneum sebum layer needed for Fipronil to translocate and establish follicular reservoirs.

• Transient Hypersalivation Notice: If an animal licks the wet product before drying, mild transient hypersalivation (excess drooling) may occur. This is primarily a physiological reaction to the bitter taste of the alcohol carrier, not systemic toxicity. It resolves spontaneously; offering clean water helps clear the taste.

Product Specifications

ParameterDetailsBrandSavavet (Sava Healthcare Limited)Product Trade NameFiprofort SprayActive IngredientFipronil 0.25% w/v (2.5 mg/ml)Chemical ClassPhenylpyrazole EctoparasiticideAvailable Packaging Sizes100 ml & 250 ml High-Density Polyethylene Bottles with Metered PumpTarget SpeciesDogs and Cats (including Puppies and Kittens from 8 weeks of age)Target ParasitesTicks (Rhipicephalus, Ixodes), Fleas (Ctenocephalides), Chewing LicePrescription StatusOTC Veterinary Ectoparasiticide Formulation (No Rx required)

Contraindications, Precautions & Storage

• Contraindicated in Rabbits: Do not use on pet rabbits or rodents. Fipronil can cause severe, life-threatening adverse reactions and mortality in rabbits.

• Sick or Convalescing Animals: Do not use on severely debilitated pets or pets with extensive open, ulcerated skin wounds without consulting a veterinarian.

• Flammability Warning: Contains an alcoholic carrier. Keep away from heat, sparks, open flames, and hot surfaces. Do not smoke during application.

• Storage Instructions: Store at room temperature (below 30°C) in a dry place away from heat, sparks, and direct sunlight. Keep the container tightly capped. Keep strictly out of reach of children and domestic pets.