Vivaldis Vet Thyro 0.2 (Levothyroxine Sodium 0.2 mg) Thyroid Hormone Replacement Tablets for Dogs & Cats

Active Composition & Pharmacodynamics

• Active Ingredient: Levothyroxine Sodium USP 0.2 mg per tablet.

• Therapeutic Class: Synthetic Endocrine Hormone / Levothyroxine (T4) Replacement.

• Mechanism of Action: Levothyroxine sodium (synthetic L-T4) distributes into the bloodstream bound to plasma carrier proteins. Intracellularly, it undergoes outer-ring deiodination into active T3 (triiodothyronine), which enters cell nuclei and binds to thyroid hormone receptors. This regulates genetic transcription of metabolic enzymes, boosting carbohydrate metabolism, protein synthesis, mitochondrial energy output, and lipid catabolism.

Target Clinical Indications

Clinical CategoryCommon Hypothyroid Signs & IndicationsMetabolic DeficienciesChronic lethargy, pronounced sluggishness, cold intolerance (heat-seeking), weight gain despite normal/reduced dietDermatological SymptomsBilateral symmetrical alopecia (flank/trunk hair loss), "rat tail" baldness, poor coat quality, recurring skin infectionsNeurological / CardiovascularBradycardia (abnormally slow heart rate), muscle weakness, mental dullnessReproductive & Age-RelatedPersistent anestrus, reproductive failure, and subclinical hypothyroid decline

Dosage & Administration Guidelines

Administer strictly according to your veterinarian’s written prescription and dose titration plan.

• General Veterinary Dosing Guidelines:

  • Initial Canine Dose: Typically 0.02 mg to 0.04 mg per kg body weight daily, administered once daily or split into two divided doses (every 12 hours).

  • Example: A 10 kg dog typically starts around 0.2 mg daily, titrated as guided by blood tests.

  • Dosing Consistency (Crucial): Administer at the same time every day. Choose either consistently with meals or consistently on an empty stomach, as food intake alters gastrointestinal absorption kinetics.

• Therapeutic Blood Monitoring:

  • Post-pill peak serum Total T4 (TT4) or Free T4 testing is recommended 4 to 8 weeks after initiating therapy or following any dosage adjustment.

  • Blood samples are typically collected 4 to 6 hours post-administration.

Product Specifications

AttributeDetailsBrandVivaldis Animal HealthProduct LineEndocrine Care / Vet ThyroActive SubstanceLevothyroxine Sodium USP 0.2 mgDosage FormOral TabletsTarget SpeciesDogs (Primary) and Cats (Under Specialist Guidance)Therapeutic ClassSynthetic Thyroid HormonePrescription StatusSchedule H Prescription Medicine (Valid Rx upload mandatory at PetMitra)

Safety Warnings & Precautions

• Signs of Thyrotoxicosis (Overdose): Excessive pacing, panting, hyperactive nervousness, tachycardia (rapid heart rate), polyuria (excessive urination), polydipsia (excessive thirst), or ravenous appetite with weight loss indicate over-supplementation. If observed, contact your veterinarian immediately to reduce dosage.

• Concurrent Health Conditions: Use with caution in pets with pre-existing congestive heart failure, cardiac arrhythmias, or hypoadrenocorticism (Addison's disease). Adrenal insufficiency must be stabilized prior to starting thyroid replacement therapy.

• Lifetime Management: Hypothyroidism is a lifelong deficiency that requires ongoing daily therapy; do not stop administering medication abruptly unless advised by your veterinary surgeon.

• Storage: Store in a cool, dry place below 25°C away from moisture, heat, and direct sunlight. Keep out of reach of children and household pets.