Intas Cefpet CLV 325mg Potentiated 3rd-Generation Cephalosporin Antibiotic Tablets for Dogs & Cats (Cefpodoxime Proxetil 200mg + Potassium Clavulanate 125mg) – Strip of 10 Tablets

Active Pharmaceutical Matrix & Pharmacological Actions (Per Tablet)

Active ConstituentStrength per TabletPharmacological ClassTherapeutic Target & Mode of ActionCefpodoxime Proxetil IPEquivalent to Cefpodoxime 200.0 mgThird-Generation CephalosporinProdrug ester metabolized to active cefpodoxime; binds bacterial PBPs to inhibit peptidoglycan cell wall synthesis, resulting in rapid bactericidal lysis.Potassium Clavulanate Diluted IPEquivalent to Clavulanic Acid 125.0 mgBeta-Lactamase Inhibitor ("Suicide Inhibitor")Binds irreversibly to plasmid- and chromosome-mediated beta-lactamases, preventing enzymatic cleavage of cefpodoxime and restoring activity against resistant strains.Tablet ExcipientsBase q.s. to 1 Uncoated TabletCompressed Oral MatrixEnsures rapid gastric disintegration, optimal intestinal absorption, and consistent drug bioavailability.

Clinical Veterinary Indications

• Complicated Skin & Soft-Tissue Infections: Deep recurrent pyoderma, generalized folliculitis, furunculosis, interdigital cysts, contaminated bite wounds, and severe feline abscesses.

• Perioperative Surgical Prophylaxis: Infection prevention before and after orthopedic procedures, fracture repairs, laparotomies, and oncologic surgeries.

• Complicated Urinary Tract Infections (UTIs): Recurrent bacterial cystitis, pyelonephritis, and prostatitis caused by beta-lactamase-producing E. coli or Proteus.

• Severe Respiratory Tract Infections: Bronchitis, bronchopneumonia, and secondary bacterial complications of kennel cough.

• Bacterial Gastrointestinal Infections: Severe bacterial enteritis and secondary mucosal infections under veterinary direction.

Comparison: Cefpet Portfolio Spectrum

Clinical MetricIntas Cefpet 100mgIntas Cefpet XL 200mgIntas Cefpet CLV 325mg (Current)Active CompositionCefpodoxime (100mg)Cefpodoxime (200mg)Cefpodoxime (200mg) + Clavulanic Acid (125mg)Beta-Lactamase InhibitorNoNoYes (Potassium Clavulanate 125mg)Primary IndicationRoutine superficial pyoderma, standard UTIsDeep pyoderma in large dogs, woundsRefractory, recurrent, or beta-lactamase-resistant infections; surgical prophylaxisDosing FrequencyOnce daily (SID)Once daily (SID)Once daily (SID) (or as directed by vet)Target Patient ProfileSmall dogs (<15 kg) & catsLarge dogs (20–40 kg)Medium-to-large dogs & cats with tough/resistant infections

Dosage & Administration Guidelines

Administer orally strictly as prescribed by your treating veterinarian based on your pet's body weight:

• Standard Veterinary Dosing Parameters (General Reference):

  • Therapeutic Range: Typically dosed at 5 mg to 10 mg Cefpodoxime per kg body weight, administered once daily (every 24 hours).

  • Each Cefpet CLV 325mg tablet contains 200 mg of active Cefpodoxime.

• Practical Reference Guide for Cefpet CLV 325mg Tablets:

Pet Body Weight RangeTypical Daily Dose (at 5–10 mg/kg Cefpodoxime basis)Clinical Context10 kg to 15 kg1/2 Tablet once dailyMedium dogs (Beagles, Cocker Spaniels, adult cats as prescribed)20 kg to 25 kg1 Tablet once dailyStandard large breeds (Labradors, Boxers, Dalmatians)30 kg to 40 kg1.5 to 2 Tablets once dailyLarge-to-giant breeds (Golden Retrievers, GSDs, Rottweilers)

• Administration Instructions:

  • Always administer with or immediately after food: Dosing alongside meals reduces transient gastrointestinal sensitivity and enhances bioavailability.

  • Can be given directly by mouth or concealed inside a small treat (boiled chicken, paneer, or wet pet food).

  • MANDATORY COURSE COMPLETION: The full prescribed course (typically 7 to 14 days for UTIs/wounds; 21 to 28 days for deep pyoderma) must be completed in full. Discontinuing treatment early when visible signs improve can promote the survival of highly resistant bacterial strains.

Product Specifications

ParameterDetailsBrandIntas Pharmaceuticals Ltd. (Intas Animal Health - PET Division)Product Trade NameCefpet CLV 325mg TabletsProduct ClassificationPotentiated Broad-Spectrum Third-Generation Cephalosporin AntibioticActive CompositionCefpodoxime Proxetil IP (eq. to Cefpodoxime 200 mg) + Potassium Clavulanate IP (eq. to Clavulanic Acid 125 mg)Dosage FormUncoated Oral TabletsPackaging SizeBlister Strip of 10 Tablets (1x10)Target SpeciesDogs and Cats across all life stagesTherapeutic ClassSystemic Antibacterial / Beta-Lactamase Resistant AntimicrobialPrescription StatusSchedule H / Veterinary Prescription Medicine (Rx required)

Safety Warnings, Precautions & Contraindications

• Prescription Only (Rx): Schedule H antibacterial. Must be dispensed and administered under veterinary supervision following a clinical diagnosis or culture-sensitivity test.

• Cephalosporin & Penicillin Hypersensitivity: Strictly contraindicated in pets with a documented history of allergic or anaphylactic reactions to cephalosporins, penicillins, or beta-lactamase inhibitors.

• Gastrointestinal Tolerability: Mild, transient digestive upset (vomiting, reduced appetite, loose stool) may occasionally occur due to the clavulanate component. Administering with a full meal typically mitigates this.

• Separate from Probiotics: When co-prescribed with probiotics (such as Intas Guts-Up), separate administration by at least 2 to 3 hours to prevent the antibiotic from inactivating live probiotic strains.

• Renal Monitoring: Use with adjusted dosing intervals in patients with severe pre-existing renal impairment.

• Not for Viral or Fungal Conditions: Ineffective against viral gastroenteritis (Parvovirus), fungal dermatophytosis (ringworm), or yeast dermatitis (Malassezia).

• Storage: Store below 25°C in a dry place protected from heat, direct sunlight, and moisture. Keep tablets sealed in their original blister foil until administration. Keep strictly out of reach of children and domestic pets.