Intas Nayflee Broad-Spectrum Ectoparasitic Contact Spray for Dogs, Puppies, Cats & Kittens – Fipronil 0.25% w/v (100ml Precision Metered Pump Spray Bottle)

Active Formulation Matrix & Pharmacological Actions

Active ConstituentConcentration (% w/v)Pharmacological ClassTarget Parasites & Biological Mode of ActionFipronil IP0.25% w/vPhenylpyrazole EctoparasiticideSelectively blocks arthropod GABA-gated & glutamate-gated chloride channels; induces fatal neuronal hyperexcitation in Ticks (Rhipicephalus), Fleas (Ctenocephalides), Lice (Trichodectes, Felicola), and Mites.Volatile Hydroalcoholic VehicleBase q.s. to 100 mlTransdermal Lipid-Spreading BaseEnhances coat wetting, dissolves epidermal sebum to aid follicular absorption, and evaporates cleanly without sticky residues.

Clinical Veterinary Indications

• Contact treatment and residual control of tick infestations (Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor spp.) in dogs and cats.

• Immediate knockdown of adult flea infestations (Ctenocephalides felis, Ctenocephalides canis).

• Eradication of biting and sucking lice (Trichodectes canis, Felicola subrostratus).

• Supportive treatment of sarcoptic mange (Sarcoptes scabiei) and cheyletiellosis (walking dandruff).

• Strategic therapeutic management of Flea Allergy Dermatitis (FAD).

• Ectoparasite control in neonatal puppies and kittens under 8 weeks of age and nursing mothers.

Comparison: Intas Nayflee Spray vs. Nayflee Plus Spot-On vs. Intas Softas Shampoo

Clinical ParameterIntas Nayflee Spray (Current)Intas Nayflee Plus Spot-OnIntas Softas Medicated ShampooActive IngredientsFipronil (0.25% w/v)Fipronil + S-Methoprene (IGR)Propoxur (1.0% w/w)Residual ProtectionUp to 30 days (Sebaceous reservoir)Up to 30 days (Full lifecycle)None (Bath-time contact kill only)Flea Life-Cycle (Eggs/Larvae)Adult contact kill onlyBreaks complete life-cycle (Kills eggs/larvae)Adult contact kill onlySafe Under 8 Weeks?YES (Safe for neonatal pups/kittens)No (Minimum 8 weeks of age)No (Minimum 4 weeks of age)Safe for Cats?YES (Fully feline-safe)Separate feline pipette availableYES (Feline-safe)Application Format100ml Precision Pump SprayTargeted topical spot-on pipetteExternal bath wash

Directions for Use & Application Protocol

For external cutaneous spray application on dogs and cats only:

The Veterinary Two-Day Priming Protocol:

1. Day 1 (Pre-Cleansing Bath): Bathe your pet using a mild routine shampoo (such as Intas Procott) to clear excessive dirt, dander, and grease. Allow the coat to dry completely.

2. Day 2 (Targeted Application): Apply Nayflee Spray 24 hours post-bath. This crucial rest interval allows natural skin sebum to replenish, ensuring optimal Fipronil absorption and distribution across the coat.

3. Application Technique:

   • Hold the bottle upright 10 cm to 20 cm from the animal's body.

   • Ruffle and part the hair coat against the natural direction of growth to spray directly onto the skin.

   • Spray the entire body evenly: neck, chest, back, flanks, abdomen, legs, and tail.

4. Facial & Ear Application: Do not spray directly onto the face. Spray a measured amount onto a gloved hand or a clean cloth and gently massage around the head, cheeks, and base of the ears, strictly avoiding the eyes, nostrils, and mouth.

5. Dosing Volume Guidelines:

   • Standard Rate: Apply 3 ml to 6 ml per kg body weight (approx. 5 to 10 trigger pumps per kg).

   • Short-coated animals: ~3 ml per kg (approx. 5 pumps/kg).

   • Dense, long, or double-coated animals: ~6 ml per kg (approx. 10 pumps/kg).

Practical Weight-to-Volume Reference Table:

Pet Body WeightCalculated Volume RangeApproximate Number of Trigger Pumps1.0 kg to 2.5 kg (Puppies/Kittens)3 ml to 10 ml5 to 16 pumps3.0 kg to 5.0 kg (Cats / Toy Dogs)10 ml to 25 ml16 to 40 pumps5.0 kg to 10.0 kg (Small Dogs)25 ml to 50 ml40 to 80 pumpsAbove 10.0 kg (Medium Dogs)50 ml to 100 ml80 to 160 pumps (or transition to spot-on/chews)

6. Post-Application Care: Allow the coat to air-dry naturally. Do not towel-dry, blow-dry, or rinse off.

7. Keep Pet Dry for 48 Hours: Do not bathe or allow the pet to swim for at least 48 hours following application to preserve sebaceous gland bonding.

Product Specifications

ParameterDetailsBrandIntas Pharmaceuticals Ltd. (NUVO Division - Animal Health)Product Trade NameNayflee Fipronil Ectoparasitic SprayProduct ClassificationBroad-Spectrum Veterinary Phenylpyrazole Contact EctoparasiticideActive CompositionFipronil IP (0.25% w/v)Dosage FormTopical Hydroalcoholic Liquid SprayPackaging Size100 ml Dispensing Bottle with Calibrated Metered PumpTarget SpeciesDogs, Cats, Puppies, Kittens, and Pregnant/Lactating FemalesTherapeutic ClassNon-Systemic Contact Ectoparasiticide / Anti-Tick, Flea & Lice SprayPrescription StatusOTC Veterinary Ectoparasitic Formulation (No Rx required)

Safety Warnings, Precautions & Contraindications

• Licking Prevention (Crucial Step): Prevent your pet from licking the treated coat until completely dry. Ingestion of the wet hydroalcoholic solution can cause transient bitter-taste hypersalivation (foaming at the mouth) and mild nausea. Use an Elizabethan collar (e-collar) or distract the animal with play for 20 to 30 minutes until the fur is dry.

• Flammable Warning: Contains a flammable hydroalcoholic base. Apply in a well-ventilated area or outdoors. Keep away from open flames, electrical heaters, and sparks until the coat has fully dried.

• Avoid Ocular & Mucosal Contact: In case of accidental contact with the eyes, flush immediately with copious clean water.

• Multi-Pet Separation: In households with multiple pets, isolate treated animals until coats are dry to prevent mutual grooming.

• Do Not Apply on Broken Skin: Avoid spraying over large, deep, open lacerations or severe chemical burns.

• Storage: Store below 25°C in a cool, dry place protected from heat and direct sunlight. Keep the bottle tightly capped and out of reach of children and domestic pets.